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Total synthesis of (+)-gelsemine via an organocatalytic Diels–Alder approach

The structurally complex alkaloid gelsemine was previously thought to have no significant biological activities, but a recent study has shown that it has potent and specific antinociception in chronic pain. While this molecule has attracted significant interests from the synthetic community, an effi...

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Vydáno v:Nat Commun
Hlavní autoři: Chen, Xiaoming, Duan, Shengguo, Tao, Cheng, Zhai, Hongbin, Qiu, Fayang G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647982/
https://ncbi.nlm.nih.gov/pubmed/25995149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8204
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