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Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome

Clustered DNA damage is defined as multiple sites of DNA damage within one or two helical turns of the duplex DNA. This complex damage is often formed by exposure of the genome to ionizing radiation and is difficult to repair. The mutagenic potential and repair mechanisms of clustered DNA damage in...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Sassa, Akira, Kamoshita, Nagisa, Kanemaru, Yuki, Honma, Masamitsu, Yasui, Manabu
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641734/
https://ncbi.nlm.nih.gov/pubmed/26559182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142218
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