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A fusion protein derived from Moraxella catarrhalis and Neisseria meningitidis aimed for immune modulation of human B cells

Moraxella IgD-binding protein (MID) is a well characterized trimeric autotransporter that specifically targets the IgD of B cells. We fused the membrane anchor of the meningococcal autotransporter NhhA with the IgD-binding region of MID (aa 962–1200) to create a chimeric protein designated as NID. T...

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Vydáno v:Hum Vaccin Immunother
Hlavní autoři: Mukherjee, Oindrilla, Singh, Birendra, Bayrak, Burcu, Jonsson, Ann-Beth, Mörgelin, Matthias, Riesbeck, Kristian
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635892/
https://ncbi.nlm.nih.gov/pubmed/26042357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1034917
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