A miRNA-based signature detected in primary melanoma tissue predicts development of brain metastasis

PURPOSE: Brain metastasis is the major cause of mortality among melanoma patients. A molecular prognostic test that can reliably stratify patients at initial melanoma diagnosis by risk of developing brain metastasis may inform the clinical management of these patients. EXPERIMENTAL DESIGN: We perfor...

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Udgivet i:Clin Cancer Res
Main Authors: Hanniford, Doug, Zhong, Judy, Koetz, Lisa, Gaziel-Sovran, Avital, Lackaye, Daniel J., Shang, Shulian, Pavlick, Anna, Shapiro, Richard, Berman, Russell, Darvishian, Farbod, Shao, Yongzhao, Osman, Iman, Hernando, Eva
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631639/
https://ncbi.nlm.nih.gov/pubmed/26089374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2566
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