Impaired platelet activation and cAMP homeostasis in MRP4-deficient mice

Molecules that reduce the level of cyclic adenosine 5′-monophosphate (cAMP) in the platelet cytosol, such as adenosine 5′-diphosphate (ADP) secreted from dense granules, trigger platelet activation. Therefore, any change in the distribution and/or availability of cyclic nucleotides or ADP may interf...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Decouture, Benoit, Dreano, Elise, Belleville-Rolland, Tiphaine, Kuci, Orjeta, Dizier, Blandine, Bazaa, Amine, Coqueran, Bérard, Lompre, Anne-Marie, Denis, Cécile V., Hulot, Jean-Sébastien, Bachelot-Loza, Christilla, Gaussem, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626663/
https://ncbi.nlm.nih.gov/pubmed/26316625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-631044
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