Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting

Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies. The regulation of Hb F levels is influenced by transcription factors. We used phylogenetic footprinting to screen transcription factors that have binding sites in HBG1 and HBG2 genes’ noncoding regions in order...

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Bibliographic Details
Published in:Evol Bioinform Online
Main Authors: de Souza Carrocini, Gisele Cristine, Venancio, Larissa Paola Rodrigues, Bonini-Domingos, Claudia Regina
Format: Artigo
Language:Inglês
Published: Libertas Academica 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624090/
https://ncbi.nlm.nih.gov/pubmed/26543346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/EBO.S15364
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