A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling

Reactive oxygen species (ROS) such as hydrogen peroxide (H(2)O(2)) govern cellular homeostasis by inducing signaling. H(2)O(2) modulates the activity of phosphatases and many other signaling molecules through oxidation of critical cysteine residues, which led to the notion that initiation of ROS sig...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Patterson, Heide Christine, Gerbeth, Carolin, Thiru, Prathapan, Vögtle, Nora F., Knoll, Marko, Shahsafaei, Aliakbar, Samocha, Kaitlin E., Huang, Cher X., Harden, Mark Michael, Song, Rui, Chen, Cynthia, Kao, Jennifer, Shi, Jiahai, Salmon, Wendy, Shaul, Yoav D., Stokes, Matthew P., Silva, Jeffrey C., Bell, George W., MacArthur, Daniel G., Ruland, Jürgen, Meisinger, Chris, Lodish, Harvey F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620870/
https://ncbi.nlm.nih.gov/pubmed/26438848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517932112
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