A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling

Reactive oxygen species (ROS) such as hydrogen peroxide (H(2)O(2)) govern cellular homeostasis by inducing signaling. H(2)O(2) modulates the activity of phosphatases and many other signaling molecules through oxidation of critical cysteine residues, which led to the notion that initiation of ROS sig...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Patterson, Heide Christine, Gerbeth, Carolin, Thiru, Prathapan, Vögtle, Nora F., Knoll, Marko, Shahsafaei, Aliakbar, Samocha, Kaitlin E., Huang, Cher X., Harden, Mark Michael, Song, Rui, Chen, Cynthia, Kao, Jennifer, Shi, Jiahai, Salmon, Wendy, Shaul, Yoav D., Stokes, Matthew P., Silva, Jeffrey C., Bell, George W., MacArthur, Daniel G., Ruland, Jürgen, Meisinger, Chris, Lodish, Harvey F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620870/
https://ncbi.nlm.nih.gov/pubmed/26438848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517932112
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