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Characterization of Dnmt1 Binding and DNA Methylation on Nucleosomes and Nucleosomal Arrays

The packaging of DNA into nucleosomes and the organisation into higher order structures of chromatin limits the access of sequence specific DNA binding factors to DNA. In cells, DNA methylation is preferentially occuring in the linker region of nucleosomes, suggesting a structural impact of chromati...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Schrader, Anna, Gross, Thomas, Thalhammer, Verena, Längst, Gernot
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619679/
https://ncbi.nlm.nih.gov/pubmed/26496704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140076
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