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Characterization of Dnmt1 Binding and DNA Methylation on Nucleosomes and Nucleosomal Arrays

The packaging of DNA into nucleosomes and the organisation into higher order structures of chromatin limits the access of sequence specific DNA binding factors to DNA. In cells, DNA methylation is preferentially occuring in the linker region of nucleosomes, suggesting a structural impact of chromati...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Schrader, Anna, Gross, Thomas, Thalhammer, Verena, Längst, Gernot
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619679/
https://ncbi.nlm.nih.gov/pubmed/26496704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140076
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