The thumb subdomain of yeast mitochondrial RNA polymerase is involved in processivity, transcript fidelity and mitochondrial transcription factor binding

Single subunit RNA polymerases have evolved 2 mechanisms to synthesize long transcripts without falling off a DNA template: binding of nascent RNA and interactions with an RNA:DNA hybrid. Mitochondrial RNA polymerases share a common ancestor with T-odd bacteriophage single subunit RNA polymerases. H...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Velazquez, Gilberto, Sousa, Rui, Brieba, Luis G
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615813/
https://ncbi.nlm.nih.gov/pubmed/25654332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1014283
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