Dose Optimization Study of AEOL 10150 as a Mitigator of Radiation-Induced Lung Injury in CBA/J Mice

AEOL 10150 is a catalytic metalloporphyrin superoxide dismutase mimic being developed as a medical countermeasure for radiation-induced lung injury (RILI). The efficacy of AEOL 10150 against RILI through a reduction of oxidative stress, hypoxia and pro-apoptotic signals has been previously reported....

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Bibliographic Details
Published in:Radiat Res
Main Authors: Murigi, Francis N., Mohindra, Pranshu, Hung, Chiwei, Salimi, Shabnam, Goetz, Wilfried, Pavlovic, Radmila, Jackson, Isabel L., Vujaskovic, Zeljko
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615610/
https://ncbi.nlm.nih.gov/pubmed/26414508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14110.1
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