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HMGA1-pseudogene overexpression contributes to cancer progression

Two pseudogenes for HMGA1, whose overexpression has a critical role in cancer progression, have been identified. They act as decoy for miRNAs that are able to target the HMGA1 gene then enhancing cell proliferation and migration. Moreover, these pseudogenes contain sequences that are potential targe...

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Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Esposito, Francesco, De Martino, Marco, Forzati, Floriana, Fusco, Alfredo
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613653/
https://ncbi.nlm.nih.gov/pubmed/25483074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.974440
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