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Investigating dynamic interdomain allostery in Pin1

Signaling proteins often sequester complementary functional sites in separate domains. How do the different domains communicate with one another? An attractive system to address this question is the mitotic regulator, human Pin1 (Lu et al., Nature 380:544–547, 1996). Pin-1 consists of two mutually t...

詳細記述

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書誌詳細
出版年:Biophys Rev
第一著者: Peng, Jeffrey W.
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610412/
https://ncbi.nlm.nih.gov/pubmed/26495045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-015-0171-9
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