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Investigating dynamic interdomain allostery in Pin1
Signaling proteins often sequester complementary functional sites in separate domains. How do the different domains communicate with one another? An attractive system to address this question is the mitotic regulator, human Pin1 (Lu et al., Nature 380:544–547, 1996). Pin-1 consists of two mutually t...
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Published in: | Biophys Rev |
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Main Author: | |
Format: | Artigo |
Language: | Inglês |
Published: |
Springer Berlin Heidelberg
2015
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Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610412/ https://ncbi.nlm.nih.gov/pubmed/26495045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-015-0171-9 |
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