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HYPOTHERMIA AND VALPROIC ACID ACTIVATE PRO-SURVIVAL PATHWAYS AFTER HEMORRHAGE

BACKGROUND: Therapeutic hypothermia (Hypo) and valproic acid (VPA, a histone deacetylase inhibitor) have independently been shown to be protective in models of trauma and hemorrhagic shock (HS), but require logistically challenging doses to be effective. Theoretically, combined treatment may further...

詳細記述

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書誌詳細
出版年:J Surg Res
主要な著者: Bambakidis, Ted, Dekker, Simone E., Liu, Baoling, Maxwell, Jake, Chatraklin, Kiril, Linzel, Durk, Li, Yongqing, Alam, Hasan B.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606462/
https://ncbi.nlm.nih.gov/pubmed/25777823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2015.02.036
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