hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway

The maintenance of genome stability is essential to prevent loss of genetic information and the development of diseases such as cancer. One of the most common forms of damage to the genetic code is the oxidation of DNA by reactive oxygen species (ROS), of which 8-oxo-7,8-dihydro-guanine (8-oxoG) is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Paquet, Nicolas, Adams, Mark N., Leong, Vincent, Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, Beard, Sam, Burgess, Joshua T., Bolderson, Emma, O'Byrne, Ken J., Richard, Derek J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2015
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605301/
https://ncbi.nlm.nih.gov/pubmed/26261212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv790
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