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Stimulation of Toll-Like Receptors profoundly influences the titer of polyreactive antibodies in the circulation

Polyreactive antibodies are a major component of the natural antibody repertoire and bind to a variety of structurally unrelated molecules. These antibodies are thought to provide a first line of defense against bacterial infections and play a major role in the clearance of apoptotic cells. What tri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Gunti, Sreenivasulu, Messer, Ronald J., Xu, Chengfu, Yan, Ming, Coleman, William G., Peterson, Karin E., Hasenkrug, Kim J., Notkins, Abner L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604466/
https://ncbi.nlm.nih.gov/pubmed/26463758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15066
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