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ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas
BAF250a (ARID1A) loss is a frequent event in high-grade endometrial cancers. It has been proposed that ARID1A is a driver gene, with ARID1A mutations occurring secondary to deregulated mismatch repair mechanism in gastric cancers, representing an alternative oncogenic pathway to p53 alteration. The...
Tallennettuna:
| Julkaisussa: | Mod Pathol |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4603563/ https://ncbi.nlm.nih.gov/pubmed/23887303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2013.144 |
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