CD47 Blockade Reduces Ischemia/Reperfusion Injury and Improves Survival in a Rat Liver Transplantation Model

Orthotopic liver transplantation (OLT) remains the standard treatment option for nonresponsive liver failure. Because ischemia/reperfusion injury (IRI) is an important impediment to the success of OLT, new therapeutic strategies are needed to reduce IRI. We investigated whether blocking the CD47/thr...

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Detalhes bibliográficos
Publicado no:Liver Transpl
Main Authors: Xiao, Zhen-Yu, Banan, Babak, Jia, Jianluo, Manning, Pamela T., Hiebsch, Ronald R., Gunasekaran, Muthukumar, Upadhya, Gundumi A., Frazier, William A., Mohanakumar, Thalachallour, Lin, Yiing, Chapman, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601606/
https://ncbi.nlm.nih.gov/pubmed/25482981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.24059
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