Gingipains from the Periodontal Pathogen Porphyromonas gingivalis Play a Significant Role in Regulation of Angiopoietin 1 and Angiopoietin 2 in Human Aortic Smooth Muscle Cells

Angiopoietin 1 (Angpt1) and angiopoietin 2 (Angpt2) are the ligands of tyrosine kinase (Tie) receptors, and they play important roles in vessel formation and the development of inflammatory diseases, such as atherosclerosis. Porphyromonas gingivalis is a Gram-negative periodontal bacterium that is t...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Zhang, Boxi, Khalaf, Hazem, Sirsjö, Allan, Bengtsson, Torbjörn
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Bacterial Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598411/
https://ncbi.nlm.nih.gov/pubmed/26283334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00498-15
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