CD47 Blockade Triggers T cell-mediated Destruction of Immunogenic Tumors

Macrophage phagocytosis of tumor cells mediated by CD47-specific blocking antibodies has been proposed to be the major effector mechanism in xenograft models. Using syngeneic immunocompetent tumor models, we reveal that in the therapeutic effects of CD47 blockade depend on dendritic cell (DC) but no...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nat Med
Huvudupphovsmän: Liu, Xiaojuan, Pu, Yang, Cron, Kyle, Deng, Liufu, Kline, Justin, Frazier, William A., Xu, Hairong, Peng, Hua, Fu, Yang-Xin, Xu, Meng Michelle
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598283/
https://ncbi.nlm.nih.gov/pubmed/26322579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3931
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk