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Translational regulation of the expression of the ubiquitin E3 ligase Nedd4–1 by mTORC1-dependent signaling

We found recently that mTORC1 regulates the biosynthesis of the ubiquitin E3 ligase Nedd4–1, but not the close homolog Nedd4–2. This regulatory process plays a key role in promoting neurite growth in neurons of the mammalian central nervous system. The molecular mechanism underlying this rather spec...

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Detalhes bibliográficos
Publicado no:Commun Integr Biol
Main Authors: Hsia, Hung-En, Kawabe, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594434/
https://ncbi.nlm.nih.gov/pubmed/26479408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420889.2015.1017161
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