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The role of the E2F1 transcription factor in the innate immune response to systemic LPS

Previous publications from our and other groups identified E2F1 as a transcription factor involved in the regulation of inflammatory response to Toll-like receptor ligands including LPS. In this study, we challenged E2F1-deficient mice with LPS systemically and demonstrated decreased survival despit...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Warg, Laura A., Oakes, Judy L., Burton, Rachel, Neidermyer, Amanda J., Rutledge, Holly R., Groshong, Steve, Schwartz, David A., Yang, Ivana V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587596/
https://ncbi.nlm.nih.gov/pubmed/22707615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00369.2011
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