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Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke

The use and effectiveness of current stroke reperfusion therapies are limited by the complications of reperfusion injury, which include increased cerebrovascular permeability and haemorrhagic transformation. Sphingosine-1-phosphate (S1P) is emerging as a potent modulator of vascular integrity via it...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Gab Seok, Yang, Li, Zhang, Guoqi, Zhao, Honggang, Selim, Magdy, McCullough, Louise D., Kluk, Michael J., Sanchez, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587559/
https://ncbi.nlm.nih.gov/pubmed/26243335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8893
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