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Rapid and transient palmitoylation of the tyrosine kinase Lck mediates Fas signaling

Palmitoylation is the posttranslational modification of proteins with a 16-carbon fatty acid chain through a labile thioester bond. The reversibility of protein palmitoylation and its profound effect on protein function suggest that this modification could play an important role as an intracellular...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Akimzhanov, Askar M., Boehning, Darren
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586849/
https://ncbi.nlm.nih.gov/pubmed/26351666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509929112
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