Bortezomib enhances the radiosensitivity of hypoxic cervical cancer cells by inhibiting HIF-1α expression

Objective: This study aimed to investigate the radiosensitivity of bortezomib to cervical cancer and the possible underlying mechanism. Methods: HeLa and SiHa cell lines with or without hypoxia treatment were divided into control, radiation alone, bortezomib alone, and radiotherapy plus bortezomib g...

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Veröffentlicht in:Int J Clin Exp Pathol
Hauptverfasser: Cui, Heqing, Qin, Qin, Yang, Meilin, Zhang, Hao, Liu, Zheming, Yang, Yan, Chen, Xiaochen, Zhu, Hongcheng, Wang, Di, Meng, Cuicui, Song, Hongmei, Ma, Jianxin, Huang, Guanhong, Cai, Jing, Sun, Xinchen, Wang, Zhongming
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583877/
https://ncbi.nlm.nih.gov/pubmed/26464645
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