Hemodynamic Effects of the Non-Peptidic Angiotensin-(1-7) Agonist AVE0991 in Liver Cirrhosis

BACKGROUND & AIMS: Although in cirrhosis with portal hypertension levels of the vasoconstrictor angiotensin II are increased, this is accompanied by increased production of angiotensin (Ang)-(1–7), the endogenous ligand of the Mas receptor (MasR), which blunts hepatic fibrosis and decreases hepa...

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Pubblicato in:PLoS One
Autori principali: Klein, Sabine, Herath, Chandana B., Schierwagen, Robert, Grace, Josephine, Haltenhof, Tom, Uschner, Frank E., Strassburg, Christian P., Sauerbruch, Tilman, Walther, Thomas, Angus, Peter W., Trebicka, Jonel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583473/
https://ncbi.nlm.nih.gov/pubmed/26406236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138732
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