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Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

BACKGROUND: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25(OH)D concentration is causally associated with bl...

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Published in:Lancet Diabetes Endocrinol
Main Authors: Vimaleswaran, Karani S, Cavadino, Alana, Berry, Diane J, Jorde, Rolf, Dieffenbach, Aida Karina, Lu, Chen, Alves, Alexessander Couto, Heerspink, Hiddo J Lambers, Tikkanen, Emmi, Eriksson, Joel, Wong, Andrew, Mangino, Massimo, Jablonski, Kathleen A, Nolte, Ilja M, Houston, Denise K, Ahluwalia, Tarunveer Singh, van der Most, Peter J, Pasko, Dorota, Zgaga, Lina, Thiering, Elisabeth, Vitart, Veronique, Fraser, Ross M, Huffman, Jennifer E, de Boer, Rudolf A, Schöttker, Ben, Saum, Kai-Uwe, McCarthy, Mark I, Dupuis, Josée, Herzig, Karl-Heinz, Sebert, Sylvain, Pouta, Anneli, Laitinen, Jaana, Kleber, Marcus E, Navis, Gerjan, Lorentzon, Mattias, Jameson, Karen, Arden, Nigel, Cooper, Jackie A, Acharya, Jayshree, Hardy, Rebecca, Raitakari, Olli, Ripatti, Samuli, Billings, Liana K, Lahti, Jari, Osmond, Clive, Penninx, Brenda W, Rejnmark, Lars, Lohman, Kurt K, Paternoster, Lavinia, Stolk, Ronald P, Hernandez, Dena G, Byberg, Liisa, Hagström, Emil, Melhus, Håkan, Ingelsson, Erik, Mellström, Dan, Ljunggren, Östen, Tzoulaki, Ioanna, McLachlan, Stela, Theodoratou, Evropi, Tiesler, Carla M T, Jula, Antti, Navarro, Pau, Wright, Alan F, Polasek, Ozren, Hayward, Caroline, Wilson, James F, Rudan, Igor, Salomaa, Veikko, Heinrich, Joachim, Campbell, Harry, Price, Jacqueline F, Karlsson, Magnus, Lind, Lars, Michaëlsson, Karl, Bandinelli, Stefania, Frayling, Timothy M, Hartman, Catharina A, Sørensen, Thorkild I A, Kritchevsky, Stephen B, Langdahl, Bente Lomholt, Eriksson, Johan G, Florez, Jose C, Spector, Tim D, Lehtimäki, Terho, Kuh, Diana, Humphries, Steve E, Cooper, Cyrus, Ohlsson, Claes, März, Winfried, de Borst, Martin H, Kumari, Meena, Kivimaki, Mika, Wang, Thomas J, Power, Chris, Brenner, Hermann, Grimnes, Guri, van der Harst, Pim, Snieder, Harold, Hingorani, Aroon D, Pilz, Stefan, Whittaker, John C, Järvelin, Marjo-Riitta, Hyppönen, Elina
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582411/
https://ncbi.nlm.nih.gov/pubmed/24974252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-8587(14)70113-5
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