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Control of mRNA Stability in Fungi by NMD, EJC and CBC Factors Through 3′UTR Introns

In higher eukaryotes the accelerated degradation of mRNAs harboring premature termination codons is controlled by nonsense-mediated mRNA decay (NMD), exon junction complex (EJC), and nuclear cap-binding complex (CBC) factors, but the mechanistic basis for this quality-control system and the specific...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Zhang, Ying, Sachs, Matthew S.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574236/
https://ncbi.nlm.nih.gov/pubmed/26048019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.176743
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