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Control of mRNA Stability in Fungi by NMD, EJC and CBC Factors Through 3′UTR Introns

In higher eukaryotes the accelerated degradation of mRNAs harboring premature termination codons is controlled by nonsense-mediated mRNA decay (NMD), exon junction complex (EJC), and nuclear cap-binding complex (CBC) factors, but the mechanistic basis for this quality-control system and the specific...

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Foilsithe in:Genetics
Main Authors: Zhang, Ying, Sachs, Matthew S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574236/
https://ncbi.nlm.nih.gov/pubmed/26048019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.176743
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