A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates

First identified in 2012, Middle East respiratory syndrome (MERS) is caused by an emerging human coronavirus, which is distinct from the severe acute respiratory syndrome coronavirus (SARS-CoV), and represents a novel member of the lineage C betacoronoviruses. Since its identification, MERS coronavi...

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Publicat a:Sci Transl Med
Autors principals: Muthumani, Karuppiah, Falzarano, Darryl, Reuschel, Emma L., Tingey, Colleen, Flingai, Seleeke, Villarreal, Daniel O., Wise, Megan, Patel, Ami, Izmirly, Abdullah, Aljuaid, Abdulelah, Seliga, Alecia M., Soule, Geoff, Morrow, Matthew, Kraynyak, Kimberly A., Khan, Amir S., Scott, Dana P., Feldmann, Friederike, LaCasse, Rachel, Meade-White, Kimberly, Okumura, Atsushi, Ugen, Kenneth E., Sardesai, Niranjan Y., Kim, J. Joseph, Kobinger, Gary, Feldmann, Heinz, Weiner, David B.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573558/
https://ncbi.nlm.nih.gov/pubmed/26290414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac7462
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