Cell lineage specificity of chromatin configuration around the immunoglobulin heavy chain enhancer.

As tested by DNase I hypersensitivity, the chromatin structure of the IgH enhancer region in human B cell precursor cell lines is in an open or accessible conformation. All T cell lines, with either germline or rearranged IgH genes, were also hypersensitive to DNase I but in contrast to B cell precu...

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Main Authors: Ford, A M, Watt, S M, Furley, A J, Molgaard, H V, Greaves, M F
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC457105/
https://ncbi.nlm.nih.gov/pubmed/2847917
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