Control of crosslinking for tailoring collagen-based scaffolds stability and mechanics

We provide evidence to show that the standard reactant concentrations used in tissue engineering to cross-link collagen-based scaffolds are up to 100 times higher than required for mechanical integrity in service, and stability against degradation in an aqueous environment. We demonstrate this with...

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Bibliographic Details
Published in:Acta Biomater
Main Authors: Davidenko, N., Schuster, C.F., Bax, D.V., Raynal, N., Farndale, R.W., Best, S.M., Cameron, R.E.
Format: Artigo
Language:Inglês
Published: Elsevier 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570933/
https://ncbi.nlm.nih.gov/pubmed/26213371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2015.07.034
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