ProNGF derived from rat sciatic nerves downregulates neurite elongation and axon specification in PC12 cells

Several reports have shown that a sciatic nerve conditioned media (CM) causes neuronal-like differentiation in PC12 cells. This differentiation is featured by neurite outgrowth, which are exclusively dendrites, without axon or sodium current induction. In previous studies, our group reported that th...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Trigos, Anna Sofía, Longart, Marines, García, Lisbeth, Castillo, Cecilia, Forsyth, Patricia, Medina, Rafael
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569732/
https://ncbi.nlm.nih.gov/pubmed/26441535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00364
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