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Requirement for Transcription Factor Ets1 in B Cell Tolerance to Self-Antigens

The differentiation and survival of autoreactive B cells is normally limited by a variety of self-tolerance mechanisms including clonal deletion, anergy and clonal ignorance. The transcription factor c-ets-1 (encoded by the Ets1 gene) has B cell-intrinsic roles in regulating formation of antibody-se...

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Pubblicato in:J Immunol
Autori principali: Russell, Lisa, John, Shinu, Cullen, Jaime, Luo, Wei, Shlomchik, Mark J., Garrett-Sinha, Lee Ann
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568556/
https://ncbi.nlm.nih.gov/pubmed/26355157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500776
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