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Alleviating neuropathic pain mechanical allodynia by increasing Cdh1 in the anterior cingulate cortex

BACKGROUND: Plastic changes in the anterior cingulate cortex (ACC) are critical in the pathogenesis of pain hypersensitivity caused by injury to peripheral nerves. Cdh1, a co-activator subunit of anaphase-promoting complex/cyclosome (APC/C) regulates synaptic differentiation and transmission. Based...

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Dettagli Bibliografici
Pubblicato in:Mol Pain
Autori principali: Tan, Wei, Yao, Wen-Long, Hu, Rong, Lv, You-You, Wan, Li, Zhang, Chuan-Han, Zhu, Chang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568074/
https://ncbi.nlm.nih.gov/pubmed/26364211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12990-015-0058-6
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