2-(3′-Indolyl)-N-arylthiazole-4-carboxamides: Synthesis and evaluation of antibacterial and anticancer activities

A new series of 2-(3′-indolyl)-N-arylthiazole-4-carboxamides 17a-p has been designed and synthesized. Initial reaction of readily available thioamides 15 with bromopyruvic acid under refluxing conditions produced different thiazole carboxylic acids 16 which upon coupling with arylamines by using EDC...

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Bibliographic Details
Published in:	Bioorg Med Chem Lett
Main Authors:	Tantak, Mukund P., Wang, Jing, Singh, Rajnish Prakash, Kumar, Anil, Shah, Kavita, Kumar, Dalip
Format:	Artigo
Language:	Inglês
Published:	2015
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4567476/ https://ncbi.nlm.nih.gov/pubmed/26298501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.07.105
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2-(3′-Indolyl)-N-arylthiazole-4-carboxamides: Synthesis and evaluation of antibacterial and anticancer activities

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