Altered Activation of Protein Kinase PKR and Enhanced Apoptosis in Dystonia Cells Carrying a Mutation in PKR Activator Protein PACT

PACT is a stress-modulated activator of the interferon-induced double-stranded RNA-activated protein kinase (PKR). Stress-induced phosphorylation of PACT is essential for PACT's association with PKR leading to PKR activation. PKR activation leads to phosphorylation of translation initiation fac...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Vaughn, Lauren S, Bragg, D. Cristopher, Sharma, Nutan, Camargos, Sarah, Cardoso, Francisco, Patel, Rekha C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566229/
https://ncbi.nlm.nih.gov/pubmed/26231208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669408
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker