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DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2
Small cell lung cancer (SCLC) is an aggressive malignancy characterized by early metastasis, rapid development of resistance to chemotherapy, and genetic instability. This study profiles DNA methylation in SCLC, patient-derived xenografts (PDXs) and cell lines at single nucleotide resolution. DNA me...
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| Publicat a: | Oncogene |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564363/ https://ncbi.nlm.nih.gov/pubmed/25746006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.38 |
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