Purification of monoclonal antibodies from clarified cell culture fluid using Protein A capture continuous countercurrent tangential chromatography

Recent studies using simple model systems have demonstrated that Continuous Countercurrent Tangential Chromatography (CCTC) has the potential to overcome many of the limitations of conventional Protein A chromatography using packed columns. The objective of this work was to optimize and implement a...

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Foilsithe in:J Biotechnol
Main Authors: Dutta, Amit K., Tran, Travis, Napadensky, Boris, Teella, Achyuta, Brookhart, Gary, Ropp, Philip A., Zhang, Ada W., Tustian, Andrew D., Zydney, Andrew L., Shinkazh, Oleg
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561037/
https://ncbi.nlm.nih.gov/pubmed/25747172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2015.02.026
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