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cAMP-dependent protein kinase inhibits α7 nicotinic receptor activity in layer 1 cortical interneurons through activation of D1/D5 dopamine receptors

Phosphorylation of ion channels, including nicotinic acetylcholine receptors (nAChRs), by protein kinases plays a key role in the modification of synaptic transmission and neuronal excitability. α7 nAChRs are the second most prevalent nAChR subtype in the CNS following α4β2. Serine 365 in the M3–M4...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Komal, Pragya, Estakhr, Jasem, Kamran, Melad, Renda, Anthony, Nashmi, Raad
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560582/
https://ncbi.nlm.nih.gov/pubmed/25990637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270469
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