A Neoglycoconjugate Containing the Human Milk Sugar LNFPIII Drives Anti-Inflammatory Activation of Antigen Presenting Cells in a CD14 Dependent Pathway

The milk pentasaccharide LNFPIII has therapeutic action for metabolic and autoimmune diseases and prolongs transplant survival in mice when presented as a neoglycoconjugate. Within LNFPIII is the Lewis(x) trisaccharide, expressed by many helminth parasites. In humans, LNFPIII is found in human milk...

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Vydáno v:PLoS One
Hlavní autoři: Tundup, Smanla, Srivastava, Leena, Norberg, Thomas, Watford, Wendy, Harn, Donald
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560409/
https://ncbi.nlm.nih.gov/pubmed/26340260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137495
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