Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide, and the biology of this cancer remains poorly understood. Recent evidence indicates that long non-coding RNAs (lncRNAs) are found to be dysregulated in a variety of cancers, including HCC. Taur...

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Опубликовано в: :Mol Cancer
Главные авторы: Huang, Ming-De, Chen, Wen-Ming, Qi, Fu-Zhen, Sun, Ming, Xu, Tong-Peng, Ma, Pei, Shu, Yong-qian
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558931/
https://ncbi.nlm.nih.gov/pubmed/26336870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0431-0
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