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Biphasic Decline of β-Cell Function with Age in Euglycemic Non-Obese Diabetic (NOD) Mice Parallels Diabetes Onset

A gradual decline in insulin response is known to precede the onset of type 1 diabetes (T1D). To track age-related changes in the β-cell function of non-obese diabetic (NOD) mice, the most commonly used animal model for T1D, and to establish differences between those who do and do not become hypergl...

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Bibliographic Details
Published in:IUBMB Life
Main Authors: Cechin, Sirlene R., Lopez-Ocejo, Omar, Karpinsky-Semper, Darla, Buchwald, Peter
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553132/
https://ncbi.nlm.nih.gov/pubmed/26099053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1391
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