Protracted Administration of L-Asparaginase in Maintenance Phase Is the Risk Factor for Hyperglycemia in Older Patients with Pediatric Acute Lymphoblastic Leukemia

Although L-asparaginase related hyperglycemia is well known adverse event, it is not studied whether the profile of this adverse event is affected by intensification of L-asparaginase administration. Here, we analyzed the profile of L-asparaginase related hyperglycemia in a 1,176 patients with pedia...

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Udgivet i:PLoS One
Main Authors: Yoshida, Hideki, Imamura, Toshihiko, Saito, Akiko M., Takahashi, Yoshihiro, Suenobu, So-ichi, Hasegawa, Daiichiro, Deguchi, Takao, Hashii, Yoshiko, Kawasaki, Hirohide, Endo, Mikiya, Hori, Hiroki, Suzuki, Nobuhiro, Kosaka, Yoshiyuki, Kato, Koji, Yumura-Yagi, Keiko, Hara, Junichi, Oda, Megumi, Sato, Atsushi, Horibe, Keizo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552641/
https://ncbi.nlm.nih.gov/pubmed/26317422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136428
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