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Abundance and specificity of influenza reactive circulating memory follicular helper and non-follicular helper CD4 T cells in healthy adults

CD4 T-cell responses are functionally complex and regulate many aspects of innate and adaptive immunity. Follicular helper (Tfh) cells are CD4 T cells specialized to support B-cell production of isotype-switched, high-affinity antibody. So far, studies of Tfh cells in humans have focused on their di...

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Bibliographic Details
Published in:Immunology
Main Authors: Leddon, Scott A, Richards, Katherine A, Treanor, John J, Sant, Andrea J
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552510/
https://ncbi.nlm.nih.gov/pubmed/26094691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12491
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