Calreticulin down-regulation inhibits the cell growth, invasion and cell cycle progression of human hepatocellular carcinoma cells

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most frequent cancers in the world. Calreticulin(CRT) is aberrantly overexpressed in many human cancer cells. The function of CRT in HCC cells remains unclear. We attempted to investigate the effects and the underlying mechanisms of CRT down-r...

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Veröffentlicht in:Diagn Pathol
Hauptverfasser: Feng, Ruo, Ye, Jianwen, Zhou, Chuang, Qi, Lei, Fu, Zhe, Yan, Bing, Liang, Zhiwei, Li, Renfeng, Zhai, Wenlong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549864/
https://ncbi.nlm.nih.gov/pubmed/26307067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0382-1
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