Genetic Interaction Between Lyn, Ets1, and Btk in the Control of Antibody Levels(,)

Tight control of B cell differentiation into plasma cells (PCs) is critical for proper immune responses and the prevention of autoimmunity. The Ets1 transcription factor acts in B cells to prevent PC differentiation. Ets1−/− mice accumulate PCs and produce autoantibodies (autoAbs). Ets1 expression i...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Mayeux, Jessica, Skaug, Brian, Luo, Wei, Russell, Lisa M., John, Shinu, Saelee, Prontip, Abbasi, Hansaa, Li, Quan-Zhen, Garrett-Sinha, Lee Ann, Satterthwaite, Anne B.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546901/
https://ncbi.nlm.nih.gov/pubmed/26209625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500165
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