Hepatotoxicity and pharmacokinetics of cisplatin in combination therapy with a traditional Chinese medicine compound of Zengmian Yiliu granules in ICR mice and SKOV-3-bearing nude mice

BACKGROUND: Cisplatin (CDDP) is a highly effective chemotherapeutic agent used for therapy of many tumors and has been limited by its toxicity. Zengmian Yiliu granule (ZMYL), a compound preparation of traditional Chinese medicines, has been used in clinic as a complementary and alternative medicine...

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Bibliographic Details
Published in:BMC Complement Altern Med
Main Authors: Gong, Can, Qian, Lin, Yang, Hong, Ji, Li-li, Wei, Hai, Zhou, Wen-bin, Qi, Cong, Wang, Chang-hong
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538754/
https://ncbi.nlm.nih.gov/pubmed/26283082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-015-0799-9
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